Chronic granulocytic leukemia, peripheral blood smear. Neutrophilia is clearly present, as is a modest shift to the left to the band stage. One myelocyte and two very abnormal eosinophils are in the field. Chromosome analysis showed the Philadelphia chromosome, t(9;22).


Blast crisis in Ph+ chronic granulocytic leukemia, peripheral blood. These blasts are extremely immature.


Polycythemia vera, bone marrow. Striking hyperplasia and increased megakaryocytes.


Hemorrhagic thrombocythemia, bone marrow biopsy stained for reticulin. The increased reticulin can be clearly appreciated by the dark strands which are seen throughout this specimen.